Harris Eric, Gillingham Bruce, Hofmeister Eric, Lyons Patrick
Orthopedic Department, Naval Medical Center San Diego, Calif 92134-1005, USA.
J Knee Surg. 2003 Jul;16(3):173-8; discussion 178.
Pigmented villonodular synovitis (PVNS) is a relatively uncommon, benign hypertrophy of synovial tissue that mimics numerous intra-articular derangements or neoplasms. Patients with PVNS present with a variety of symptoms. Pigmented villonodular synovitis may exist in other orthopedic pathology, making it a difficult diagnosis without histologic examination. This article presents three unusual cases of localized PVNS involving the knee, including one lesion arising from the popliteal tendon, which is previously unreported in the orthopedic literature. These cases illustrate the protean manifestations of PVNS as well as the variety of methods necessary to treat it. A brief discussion of PVNS including proposed etiologies, clinical presentation, description of the histologic and radiographic characteristics of the lesion, and its treatment are included.
色素沉着绒毛结节性滑膜炎（PVNS）是一种相对罕见的滑膜组织良性增生，可模仿多种关节内紊乱或肿瘤。PVNS患者表现出多种症状。色素沉着绒毛结节性滑膜炎可能存在于其他骨科病理情况中，若无组织学检查则难以诊断。本文介绍了三例累及膝关节的局限性PVNS的不寻常病例，其中一例病变起源于腘肌腱，这在骨科文献中此前未见报道。这些病例说明了PVNS的多种表现形式以及治疗所需的多种方法。文中还简要讨论了PVNS，包括提出的病因、临床表现、病变的组织学和影像学特征描述及其治疗。
