Lteif Amale A, Mather Kieren J, Clark Charles M
Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Cardiol Rev. 2003 Sep-Oct;11(5):262-74. doi: 10.1097/01.crd.0000086892.07437.05.
Type 2 diabetes is a worldwide epidemic. Cardiovascular diseases remain the major cause of death in patients with diabetes, partly because of the association of diabetes and the metabolic syndrome. In this review, we will discuss the evidence for treatment and prevention of cardiovascular diseases in patients with diabetes. Aggressive treatment of hypertension and dyslipidemia is at the cornerstone in the management of heart disease in those patients. Despite its known benefit on the prevention of the microvascular complications of diabetes, intensive glycemic control may or may not have a significant effect on reducing macrovascular diseases. Finally, lifestyle changes and other cardiovascular therapies aimed at preventing heart disease may also prevent or delay the development of diabetes.
2型糖尿病是一种全球性的流行病。心血管疾病仍然是糖尿病患者的主要死因，部分原因是糖尿病与代谢综合征相关。在本综述中，我们将讨论糖尿病患者心血管疾病治疗和预防的证据。积极治疗高血压和血脂异常是这些患者心脏病管理的基石。尽管强化血糖控制对预防糖尿病微血管并发症有已知益处，但它对减少大血管疾病可能有显著影响，也可能没有。最后，旨在预防心脏病的生活方式改变和其他心血管治疗也可能预防或延缓糖尿病的发生。
