Turner Mark O
Peace Arch Hospital, White Rock, British Columbia, Vancouver.
Can Respir J. 2003 Jul-Aug;10(5):278-9. doi: 10.1155/2003/230982.
A 47-year-old man presented with an eight-day history of nonproductive cough and constitutional symptoms progressing to respiratory failure. High resolution computed tomography revealed a diffuse micronodular pattern and a 'tree-in-bud' pattern in the lower lung zones. Transbronchial biopsy showed features consistent with bronchiolitis obliterans organizing pneumonia (BOOP). After an initially difficult clinical course, the patient responded well to long term treatment with corticosteroids, including improvement of air flow obstruction. This case illustrates a variant of BOOP characterized by a comparatively acute onset, a component of proliferative bronchiolitis, an obstructive rather than restrictive pattern of pulmonary function testing and good clinical response to corticosteroid therapy.
一名47岁男性，有8天干咳及全身症状病史，后进展为呼吸衰竭。高分辨率计算机断层扫描显示下肺野有弥漫性微结节影及“树芽征”。经支气管活检显示的特征符合闭塞性细支气管炎伴机化性肺炎（BOOP）。在经历了最初艰难的临床过程后，患者对长期使用皮质类固醇治疗反应良好，包括气流阻塞得到改善。该病例说明了BOOP的一种变体，其特点是起病相对较急，有增殖性细支气管炎成分，肺功能测试呈阻塞性而非限制性模式，且对皮质类固醇治疗有良好的临床反应。
