Hanon O, Hoguin J C, Girerd X
Service d'endocrinologie métabolisme, hôpital Pitié-Salpêtrière, 83, bd de l'Hôpital, 75013 Paris.
Arch Mal Coeur Vaiss. 2003 Jul-Aug;96(7-8):744-7.
The French guidelines of the 2000 ANAES indicate that the management of patients with hypertension should not be based only on the level of blood pressure, but also on the presence of other risk factors and/or concomitant diseases such as diabetes or target organ damage.
To evaluate if the 2000 ANAES Guidelines concerning the initiation of antihypertensive treatment are applied by general practitioners.
Seventy new diagnosed hypertensive subjects, never treated by antihypertensive drugs, managed by 13 general practitioners were included in the study. From the data of the general practitioners medical report, the cardiovascular risk have been retrospectively recalculated for all the subjects. The concordance between the Guidelines and the clinical practice in term of institution of treatment have been evaluated.
In this population of mean age 58 +/- 15 years, a concordance of 64% between the 2000 ANAES Guidelines and the clinical practice was observed (45/70 subjects). Among the discordant subjects (36%, [25/70]), the treatment was instituted by excess in 88% of cases (22/25) although it was not recommended. In contrast, in the remaining 12% of cases, only lifestyle measures have been proposed although an antihypertensive treatment was recommended. The discordance concerns essentially subjects with medium cardiovascular risk (84%). The principal determinants of this discordance were the grade 2 of hypertension and the presence of few risk factors (1 or 2), where the cardiovascular risk have been overestimated.
Guidelines concerning the initiation of antihypertensive treatment in new diagnosed hypertensive subjects are more often applied by general practitioners. It is particularly in subjects with medium cardiovascular risk that the decision of the initiation of treatment is taken by excess in comparison to guidelines.
2000年法国麻醉与重症监护学会(ANAES)指南指出,高血压患者的管理不应仅基于血压水平,还应考虑其他危险因素和/或并存疾病,如糖尿病或靶器官损害。
评估全科医生是否应用了2000年ANAES关于启动降压治疗的指南。
本研究纳入了由13名全科医生管理的70名新诊断的高血压患者,这些患者从未接受过降压药物治疗。根据全科医生的医疗报告数据,对所有受试者的心血管风险进行了回顾性重新计算。评估了指南与治疗启动方面临床实践之间的一致性。
在这个平均年龄为58±15岁的人群中,观察到2000年ANAES指南与临床实践之间的一致性为64%(45/70名受试者)。在不一致的受试者中(36%,[25/70]),88%的病例(22/25)治疗启动过度,尽管并不推荐。相反,在其余12%的病例中,尽管推荐了降压治疗,但仅提出了生活方式措施。不一致主要涉及心血管风险中等(84%)的受试者。这种不一致的主要决定因素是2级高血压和危险因素较少(1或2个)的情况,此时心血管风险被高估。
全科医生更常应用关于新诊断高血压患者启动降压治疗的指南。特别是在心血管风险中等的受试者中,与指南相比,治疗启动的决定过度。