Song Z J, Liu B Y, Qian X H, Yang S C, Wei K H, Zheng Y H, Ma X, Zhang H B
National Center of Biomedical Analysis, Beijing 100850, China.
Guang Pu Xue Yu Guang Pu Fen Xi. 2001 Oct;21(5):603-6.
In this paper, the iodine beta-cyclodextrin complexes prepared in different techniques were investigated by Fourier transformation infrared spectrum(FTIR), FT-Raman, Ultra-violet absorption spectrum in qualitative and quantitative analysis. Results showed that the iodine existed in dissociated, bundle and polymerized forms in the complexes. Contras to the method of alcohol craft, the sample prepared in water craft method included a higher capacity of iodine, but it was not stable enough to keep a constant high iodine concentration. This analysis method was simple and convenient, it is useful for quality control of the iodine beta-cyclodextrin complexes raw material medicine.
本文采用傅里叶变换红外光谱（FTIR）、傅里叶变换拉曼光谱、紫外吸收光谱对不同工艺制备的碘-β-环糊精复合物进行了定性和定量分析。结果表明，复合物中的碘以解离、束状和聚合形式存在。与醇法相比，水法制备的样品碘含量较高，但保持高碘浓度的稳定性不足。该分析方法简单方便，可用于碘-β-环糊精复合物原料药的质量控制。
