Zhao G Z, Li H K, Liu Y, Mu W
Jinzhou Medical College, Jinzhou 121000, China.
Guang Pu Xue Yu Guang Pu Fen Xi. 2001 Oct;21(5):733-4.
The charge transfer reaction between clotrimazolum and alizarin red was studied spectrophotometrically. The reaction was achieved with good results in water-acetone solution. The apparent molar absorptivity is 8.7 x 10(3) L.mol-1.cm-1 at 525 nm. The Beer's law was obeyed in the range of 0-100 micrograms.mL-1 of clotrimazolum. The composition of the complex is 1:1. The proposed method has been applied successfully to the determination of clotrimazolum tablets.
采用分光光度法研究了克霉唑与茜素红之间的电荷转移反应。该反应在水 - 丙酮溶液中进行，效果良好。在525nm处的表观摩尔吸光系数为8.7×10³L·mol⁻¹·cm⁻¹。在0 - 100μg·mL⁻¹的克霉唑浓度范围内符合比尔定律。配合物的组成比为1:1。该方法已成功应用于克霉唑片剂的测定。
