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[Synthesis and DNA binding studies of Ruthenium complexes by spectra].

作者信息

Wu M, Song G, Ling L, He Z, Zeng Y

机构信息

Analysis and Testing Center, Hubei University, 430062 Wuhan.

出版信息

Guang Pu Xue Yu Guang Pu Fen Xi. 2000 Aug;20(4):575-6.

PMID:12945382
Abstract

New Complexes Ru(bpy)2dppx2+ were synthesized. The binding of Ru(bpy)2dppx2+ to calf thymus DNA has been investigated by using electronic absorption and fluorescence spectra. The intercalation mode was proved to exist. The DNA leads to a dramatic enhancement of the photoluminescence of the drug at 599 nm (lambda ex = 471 nm) and absorption hypochromic effect and red shift. It was obvious that Ruthenium complexes may be used at a good DNA probe.

摘要

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