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[肠道类癌肿瘤的外科治疗]

[Surgical treatment of carcinoid tumors of the intestine].

作者信息

Simon D, Goretzki P E, Branscheid D, Röher J D

机构信息

Département de Chirurgie Générale et Traumatologique, Clinique Chirurgicale Universitaire de Düsseldorf.

出版信息

J Chir (Paris). 1992 Oct;129(10):449-55.

PMID:1294589
Abstract

Carcinoid tumours arise from the neuroendocrine system and present a characteristic morphological picture. They occur in almost every organ, predilected sites are the appendix and the small intestine. Prognosis depends on the primary localization and tumour size. Carcinoids of the appendix and rectum are mostly small and thus have a good prognosis. Growth of bronchial, stomach and small intestinal carcinoids is aggressive and implicates a high percentage of metastatic disease. First choice therapy is the surgical removal of the tumour. Depending on tumour size surgical treatment includes fulguration, local excision and oncologic radical resection up to extended organ extirpation. Reoperation and repeated surgery have good chances to be successful concerning tumour remission and improvement of the carcinoid syndrome. Additive treatment comprises in particular somatostatin therapy and, in some cases, chemotherapy.

摘要

类癌肿瘤起源于神经内分泌系统,呈现出特征性的形态学表现。它们几乎可发生于每个器官,好发部位是阑尾和小肠。预后取决于原发部位和肿瘤大小。阑尾和直肠类癌大多较小,因此预后良好。支气管、胃和小肠类癌生长侵袭性强,转移疾病发生率高。首选治疗方法是手术切除肿瘤。根据肿瘤大小,手术治疗包括电灼、局部切除以及直至扩大器官切除的肿瘤根治性切除。再次手术和重复手术在肿瘤缓解和类癌综合征改善方面有很大成功机会。辅助治疗尤其包括生长抑素治疗,在某些情况下还包括化疗。

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