Andåker L, Lamke L O, Smeds S
Acta Chir Scand. 1985;151(5):469-73.
A series of 102 patients with carcinoid tumor is reviewed. The sites of carcinoid were stomach (1 case), appendix (32), small intestine (57) and colon or rectum (12). The average age was 37 years in the patients with appendiceal carcinoid and 62 years in the others. The mean observation time was 9.2 years in appendiceal carcinoid, and none of these patients died of the tumor. Among the patients with carcinoid in other sites, the 5-year survival rate was 65%. Only patients initially free from metastases were still alive after 12 years. Multiple synchronous carcinoid tumors were found in 14 cases, all of them men. The investigation illustrated the difficulties in preoperative diagnosis of carcinoid, including the small value of laboratory tests. A positive attitude to exploratory laparotomy is therefore recommended. When no or only a few lymph-node metastases are found at intendedly curative operation, a "second look" exploration six months after the primary operation will probably reveal any recurrence and can lead to radical removal of this slow-growing tumor. When distant metastases are present, the long-term outlook is poor. The reason why only men had multiple synchronous carcinoids was not clear from our study.
回顾了102例类癌患者的情况。类癌的发病部位为胃（1例）、阑尾（32例）、小肠（57例）和结肠或直肠（12例）。阑尾类癌患者的平均年龄为37岁，其他部位类癌患者的平均年龄为62岁。阑尾类癌患者的平均观察时间为9.2年，这些患者均未死于该肿瘤。在其他部位类癌患者中，5年生存率为65%。只有最初无转移的患者在12年后仍存活。14例患者发现有多发性同时性类癌肿瘤，均为男性。该调查说明了类癌术前诊断的困难，包括实验室检查价值不大。因此，建议对剖腹探查持积极态度。当在预期的根治性手术中未发现或仅发现少数淋巴结转移时，在初次手术后6个月进行“二次探查”可能会发现任何复发情况，并可导致彻底切除这种生长缓慢的肿瘤。当存在远处转移时，长期预后较差。从我们的研究中尚不清楚为何只有男性有多发性同时性类癌。
