Kutok Jeffery L, Fletcher Christopher D M
Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Semin Diagn Pathol. 2003 May;20(2):128-39. doi: 10.1016/s0740-2570(03)00011-x.
Splenic vascular tumors are uncommon and are more typically encountered as benign incidental findings. By contrast, splenic angiosarcoma may present acutely and dramatically and typically pursues a very aggressive clinical course. Vascular tumors in the spleen may show conventional endothelial, specialized endothelial (sinusoidal/littoral cell) or lymphatic differentiation and there is morphologic overlap between some of the currently defined diagnostic categories, within which benign, intermediate, and malignant subsets are recognized. The greatest problem in trying to better define and analyze these tumors is the availability of only relatively small case numbers. This overview describes the diagnosis and differential diagnosis of splenic vascular tumors as presently understood.
脾脏血管肿瘤并不常见，更常见的是作为良性偶然发现。相比之下，脾脏血管肉瘤可能急性且显著地出现，并且通常具有非常侵袭性的临床病程。脾脏中的血管肿瘤可能表现为传统内皮、特殊内皮（窦状/边缘细胞）或淋巴管分化，并且在一些当前定义的诊断类别之间存在形态学重叠，其中可识别出良性、中间型和恶性亚组。试图更好地定义和分析这些肿瘤的最大问题是仅有相对较少的病例数。本综述描述了目前所理解的脾脏血管肿瘤的诊断和鉴别诊断。
