Sheen-Chen S M, Chou F F, Chen Y S, Chen M J, Chen F C, Chen J J, Wan Y L
Department of Surgery, Chang Gung Memorial Hospital, Chang Gung Medical College, Kaohsiung Hsien, Taiwan, Republic of China.
J Clin Gastroenterol. 1992 Dec;15(4):302-5. doi: 10.1097/00004836-199212000-00007.
Between January 1986 and November 1990, 231 patients underwent resection for primary gastric adenocarcinoma at Chang Gung Memorial Hospital in southern Taiwan. Thirty-nine (17%) of these patients had early gastric cancer (limited to the mucosa or submucosa regardless of nodal metastases). Epigastric pain was the most frequent symptom (71.8%). The lesions were located in the lower third of the stomach in 84.6% of the patients and in the middle third in 15.4%. A preoperative diagnosis of gastric cancer was achieved in 94% of patients by endoscopic examination with biopsies. All of the patients underwent distal subtotal gastrectomy without mortality. Macroscopically, 84.6% of cases were included in types IIc, III, and IIc-III. One patient died of multiple liver metastases 3.2 years after operation. The cumulative survival rate at 5 years is 92.9%. We comment on these matters and place early gastric cancer in Taiwan into a more global context.
1986年1月至1990年11月期间,231例患者在台湾南部的长庚纪念医院接受了原发性胃腺癌切除术。其中39例(17%)为早期胃癌(局限于黏膜或黏膜下层,无论有无淋巴结转移)。上腹部疼痛是最常见的症状(71.8%)。84.6%的患者病变位于胃的下三分之一,15.4%位于胃的中三分之一。94%的患者通过内镜检查及活检实现了术前胃癌诊断。所有患者均接受了远端胃大部切除术,无死亡病例。肉眼观察,84.6%的病例属于Ⅱc型、Ⅲ型和Ⅱc-Ⅲ型。1例患者术后3.2年死于多发肝转移。5年累计生存率为92.9%。我们对这些情况进行了评论,并将台湾的早期胃癌纳入更广泛的全球背景中。