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瑞士儿童尿路感染后膀胱输尿管反流诊断建议的实施情况

Implementation of recommendations in the diagnosis of vesicoureteric reflux after urinary tract infections in Swiss children.

作者信息

Langanke Konstanze, Sager Michael, Giger Andreas, Simonetti Giacomo D, Marra Giuseppina, Bianchetti Mario G

机构信息

Division of Nephrology, University Children's Hospital, Inselspital, Bern, Switzerland.

出版信息

Swiss Med Wkly. 2003 Jul 12;133(27-28):385-7. doi: 10.4414/smw.2003.10251.

Abstract

BACKGROUND

Efforts are now routinely made for early detection of vesicoureteric reflux after urinary tract infections in order to limit secondary renal damage.

METHODS

The age at diagnosis of reflux after urinary tract infections was analysed in 162 Swiss patients (46 boys and 116 girls) referred by primary care physicians to the Division of Paediatric Nephrology, University of Bern, Switzerland between 1978 and 1999. The figures noted in Switzerland were also compared with those noted in 102 Australian patients (35 boys and 67 girls) reported by Lenaghan in 1976.

RESULTS

In Switzerland the median age at diagnosis was 23 months in 74 subjects diagnosed between 1978 and 1988 and 10 months in 88 subjects diagnosed between 1989 and 1999. The difference was statistically significant in girls but not in boys. In Australia the median age at diagnosis was 15 months for boys and 78 months for girls; in Switzerland, the corresponding figures were 12 and 29 months (between 1978 and 1988), respectively 5 and 14 months (between 1989 and 1999). The difference between Australia and Switzerland was statistically significant in girls but not in boys.

CONCLUSIONS

In Switzerland vesicoureteric reflux is now detected earlier than in the past. This trend is more marked in girls than in boys but the detection of reflux is still earlier in boys than in girls.

摘要

背景

目前常规采取措施在尿路感染后尽早检测膀胱输尿管反流,以限制继发性肾损害。

方法

分析了1978年至1999年间由初级保健医生转诊至瑞士伯尔尼大学儿科肾病科的162例瑞士患者(46例男孩和116例女孩)尿路感染后反流诊断时的年龄。还将瑞士记录的数据与1976年Lenaghan报告的102例澳大利亚患者(35例男孩和67例女孩)的数据进行了比较。

结果

在瑞士,1978年至1988年间诊断的74例患者诊断时的中位年龄为23个月,1989年至1999年间诊断的88例患者为10个月。女孩中的差异具有统计学意义,男孩中则无。在澳大利亚,男孩诊断时的中位年龄为15个月,女孩为78个月;在瑞士,相应数字分别为12个月和29个月(1978年至1988年间),以及5个月和14个月(1989年至1999年间)。澳大利亚和瑞士之间女孩的差异具有统计学意义,男孩中则无。

结论

在瑞士,目前膀胱输尿管反流的检测比过去更早。这种趋势在女孩中比在男孩中更明显,但男孩反流的检测仍比女孩更早。

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