[腹水抗结核及腺苷脱氨酶检测在鉴别结核性腹水与癌性腹水中的应用]
[The tests for anti-TB and adenosine deaminase in ascites for distinguishing between tuberculous ascites and carcinous ascites].
作者信息
Yang Zhengbing, Xiang Dansha, Fu Mingjian
机构信息
Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu 610041, China.
出版信息
Sichuan Da Xue Xue Bao Yi Xue Ban. 2003 Apr;34(2):320-1.
OBJECTIVE
To evaluate the tests for anti-TB and adenosine deaminase (ADA) in ascites in an attempt to distinguish between tuberculous ascites and carcinous ascites.
METHODS
DIGFA was used to test anti-TB and Martineck's method was used to determine the level of ADA in 35 cases of tuberculous ascites and 31 cases of carcinous ascites.
RESULTS
The levels of anti-TB and ADA in ascites were significantly higher in tuberculous ascites than those in carcinous ascites (P < 0.01). When the level of ADA was higher than 45 U/L, the sensitivity, specificity and accuracy in the diagnosis of tuberculous ascites were 100%, 97.1% and 98.5%, respectively. When the result of anti-TB test was positive, the sensitivity, specificity and accuracy in the diagnosis of tuberculous ascites were 93.5%, 94.3% and 95.38%, respectively.
CONCLUSION
The tests for anti-TB and ADA in ascites are of important clinical value to differential diagnosis in an attempt to distinguish between tuberculous ascites and carcinous ascites.
目的
评估腹水抗结核及腺苷脱氨酶（ADA）检测，以鉴别结核性腹水和癌性腹水。
方法
采用斑点免疫金渗滤法检测35例结核性腹水及31例癌性腹水的抗结核情况，采用马丁内克法测定ADA水平。
结果
结核性腹水腹水中抗结核及ADA水平显著高于癌性腹水（P<0.01）。当ADA水平高于45 U/L时，诊断结核性腹水的敏感度、特异度及准确度分别为100%、97.1%及98.5%。当抗结核检测结果为阳性时，诊断结核性腹水的敏感度、特异度及准确度分别为93.5%、94.3%及95.38%。
结论
腹水抗结核及ADA检测对鉴别结核性腹水和癌性腹水的临床诊断具有重要价值。
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