Morris David L, Kroker George F, Sabnis Vijay K, Morris Mary S
Allergy Associates of La Crosse, Ltd., La Crosse, Wisc 54602-2408, USA.
Chem Immunol Allergy. 2003;82:1-10. doi: 10.1159/000071537.
Specific immunotherapy is a very powerful tool which is currently underutilized in the treatment of allergies. Sublingual immunotherapy (SLIT) has many advantages over subcutaneous immunotherapy (SCIT), and has been well proven to work for many pollens and dust mites. Multiple studies have shown SLIT improves symptoms and reduces the reliance on medications. Sublingual treatment has been studied in Europe and is endorsed by the World Health Organization Committee on Immunotherapy as a viable alternative to SCIT.
SLIT offers another option for patients who are not currently candidates for subcutaneous immunotherapy. Because of improved safety, convenience and compliance, sublingual immunotherapy should be used as a first-line treatment option.
特异性免疫疗法是一种非常强大的工具，目前在过敏治疗中未得到充分利用。舌下免疫疗法（SLIT）相较于皮下免疫疗法（SCIT）具有许多优势，并且已被充分证明对多种花粉和尘螨有效。多项研究表明，SLIT可改善症状并减少对药物的依赖。舌下治疗已在欧洲进行研究，并得到世界卫生组织免疫疗法委员会的认可，作为SCIT的可行替代方案。
SLIT为目前不适合皮下免疫疗法的患者提供了另一种选择。由于安全性提高、便利性和依从性好，舌下免疫疗法应作为一线治疗选择。
