Issa Naoum P
Department of Neurobiology, Pharmacology and Physiology, The University of Chicago, 947 E. 58th Street MC 0926, Chicago, Illinois 60637, USA.
Trends Neurosci. 2003 Sep;26(9):456-8. doi: 10.1016/S0166-2236(03)00209-1.
Inhibitory and excitatory connections are equal partners in determining neuronal response properties. Although the development and plasticity of excitatory networks have been heavily studied, little is known about how inhibitory circuits develop. In a recent study, Gunsoo Kim and Karl Kandler have shown that, as in the development of excitatory circuits, synapse elimination and strengthening are important processes for the development of well-organized inhibitory circuits.
抑制性连接和兴奋性连接在决定神经元反应特性方面起着同等重要的作用。尽管兴奋性神经网络的发育和可塑性已得到深入研究，但对于抑制性回路如何发育却知之甚少。在最近的一项研究中，金均秀（Gunsoo Kim）和卡尔·坎德勒（Karl Kandler）表明，与兴奋性回路的发育一样，突触消除和增强是发育出组织良好的抑制性回路的重要过程。
