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[CBA和C57BL小鼠及其杂种染色体核仁组织区的细胞学研究]

[Cytological study of the nucleolus organizer regions in the chromosomes of CBA and C57BL mice and their hybrids].

作者信息

Patkin E L, Kustova M E, Dyban A P

出版信息

Ontogenez. 1992 Nov-Dec;23(6):632-7.

PMID:1294927
Abstract

Transcriptionally active NORs of chromosomes visualized by AgNO3 staining were studied in bone marrow and embryos (day 10 of gestation) of CBA and C57BL mice, as well as of (CBA x C57BL)F1 hybrids. These mouse strains were shown to differ by the average number of Ag-positive NORs in marrow cells; in hybrids, the number of NORs is greater than in the parent strains. During embryogenesis, the number of chromosomes carrying silver-stained NORs increases; however, no significant differences by this parameter was detected between hybrid and C57BL embryos. The average number of silver-stained NORs was the smallest in embryos of CBA mice.

摘要

通过硝酸银染色可视化的染色体转录活性核仁组织区,在CBA和C57BL小鼠以及(CBA×C57BL)F1杂种的骨髓和胚胎(妊娠第10天)中进行了研究。这些小鼠品系显示出骨髓细胞中银阳性核仁组织区的平均数量存在差异;在杂种中,核仁组织区的数量比亲本品系更多。在胚胎发生过程中,携带银染核仁组织区的染色体数量增加;然而,在杂种胚胎和C57BL胚胎之间,未检测到该参数的显著差异。CBA小鼠胚胎中银染核仁组织区的平均数量最少。

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