Myagkova M A, Abramenko T V, Panchenko O N, Epstein O I
Institute of Physiologically Active Substances, Russian Academy of Sciences, Chernogolovka.
Bull Exp Biol Med. 2003 Jan;135 Suppl 7:102-4. doi: 10.1023/a:1024759503580.
The effects of potentiated homeopathic preparations containing antibodies to delta sleep-inducing peptide in ultralow doses were studied by enzyme immunoassay. Experiments were performed with the following immunochemical reagents: antigens of delta sleep-inducing peptide conjugated to various macromolecular carriers and specific antigens. Antibodies to delta sleep-inducing peptide were synthesized in dilutions of C3, C6, C12, C50, and C200. Enzyme immunoassay showed that test preparations of antibodies in dilutions of 1:400-1:3200 produce the combined effect on immune complex formation. The proposed method holds much promise for identification of medicinal preparations in ultralow doses.
采用酶免疫测定法研究了超低剂量含δ睡眠诱导肽抗体的顺势强化制剂的效果。使用以下免疫化学试剂进行实验:与各种大分子载体偶联的δ睡眠诱导肽抗原和特异性抗原。在C3、C6、C12、C50和C200稀释液中合成了δ睡眠诱导肽抗体。酶免疫测定表明,1:400 - 1:3200稀释液中的抗体测试制剂对免疫复合物形成产生联合作用。所提出的方法在鉴定超低剂量药物制剂方面具有很大前景。