CT引导下放射性核素立体定向注射治疗脑肿瘤。

CT-guided stereotactic injection of radionuclide for treatment of brain tumors.

作者信息

Tian Z M, Liu Z H, Kang G Q, Zhang Y, Li S Y, Chen X H, Chui Y, Feng H

机构信息

Department of Neurosurgery, Yan Jing Medical Institute, Beijing, People's Republic of China.

出版信息

Stereotact Funct Neurosurg. 1992;59(1-4):169-73. doi: 10.1159/000098936.

DOI:10.1159/000098936

PMID:1295037

Abstract

The authors report on 40 brain tumor patients treated with CT-guided stereotactic injection of 198Au and 32P. Among the 40 cases were astrocytoma in 23 cases, craniopharyngioma in 9, meningioma in 4, pituitary adenoma in 2, and pinealoma and metastatic carcinoma each in 1 case. The tumors were all located in deep or important areas of the brain which were difficult to deal with by conventional operation. 62 injections of colloidal isotopes were performed, and all were successful. No major adverse effects or complications occurred on follow-up of 6-12 months, 28 patients were improved in their clinical symptoms, and CT scanning showed that the tumor sizes were diminished. The effective rate is 70%.

摘要

作者报告了40例接受CT引导下立体定向注射198Au和32P治疗的脑肿瘤患者。40例中，星形细胞瘤23例，颅咽管瘤9例，脑膜瘤4例，垂体腺瘤2例，松果体瘤和转移癌各1例。肿瘤均位于脑深部或重要区域，难以通过传统手术处理。共进行了62次胶体同位素注射，均获成功。随访6 - 12个月未出现重大不良反应或并发症，28例患者临床症状改善，CT扫描显示肿瘤体积缩小。有效率为70%。