Tian Z M, Liu Z H, Kang G Q, Li S Y, Wang Y G, Diao G P, Dong G Z
Department of Neurosurgery, Navy General Hospital, Beijing.
Chin Med J (Engl). 1992 Dec;105(12):987-91.
140 patients with brain tumor were treated by CT-guided stereotactic injections of radionuclides, such as Aurum-198 (198 Au), Phosphorus-32 (32 P) and Yttrium-90 (90Y). Of these patients aged from 3 to 67 years (average 37), 64 were male and 76 female. Astrocytoma was found in 75 patients, craniopharyngioma in 46, metastatic carcinoma in 7, meningioma in 5, germinoma in 4 and pituitary adenoma in 3. The tumors were located in the deep part or functionally critical area of the brain. After 267 times of injection of colloidal isotopes, no major adverse effects or complications occurred. Follow-up for 6 to 48 months showed improvement in symptoms in 104 (74.3%) patients and CT scanning showed the diminished tumors.
140例脑肿瘤患者接受了CT引导下放射性核素的立体定向注射治疗，所用放射性核素包括金-198（198Au）、磷-32（32P）和钇-90（90Y）。这些患者年龄在3至67岁之间（平均37岁），男性64例，女性76例。其中星形细胞瘤75例，颅咽管瘤46例，转移癌7例，脑膜瘤5例，生殖细胞瘤4例，垂体腺瘤3例。肿瘤位于脑深部或功能关键区。在进行267次胶体同位素注射后，未出现重大不良反应或并发症。6至48个月的随访显示，104例（74.3%）患者症状改善，CT扫描显示肿瘤缩小。
