Pérez-Ferrer A, De Vicente J, Gredilla E, García-Vega M I, Bourgeois P, Goldman L J
The Department of Paediatric Anaesthesiology, La Paz Children's University Hospital, Madrid, Spain.
Paediatr Anaesth. 2003 Sep;13(7):633-6. doi: 10.1046/j.1460-9592.2003.01012.x.
We present a case of surgery in a 2-month-old infant of the Jehovah's Witness (JW) faith weighing 2.8 kg scheduled for left upper lobectomy because of congenital lobar emphysema. He presented with physiological anaemia (haematocrit 33.8%) in accordance with his age. Because of the relative emergency of surgery, a short erythropoietin course was instituted. Recombinant human erythropoietin (rHuEPO) at a dosage of 180 U x kg-1x day-1 was administered for 10 days preoperatively and for 4 days postoperatively. Iron was administered orally and intravenously over the entire perioperative period. No side-effects from either erythropoietin or intravenously administered iron were observed. To our knowledge, this is the first case published of a short perioperative rHuEPO course in an infant.
我们报告一例2个月大、体重2.8kg的耶和华见证会（JW）信徒婴儿的手术病例，该婴儿因先天性大叶性肺气肿计划行左上肺叶切除术。他出现了符合其年龄的生理性贫血（血细胞比容33.8%）。由于手术相对紧急，因此采用了短期促红细胞生成素治疗方案。术前10天及术后4天给予剂量为180U·kg⁻¹·天⁻¹的重组人促红细胞生成素（rHuEPO）。在整个围手术期口服并静脉给予铁剂。未观察到促红细胞生成素或静脉注射铁剂的任何副作用。据我们所知，这是首次发表的婴儿围手术期短期使用rHuEPO的病例。
