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[家族性高胆固醇血症的部分回肠旁路手术]

[Partial ileal bypass for familial hypercholesterolemia].

作者信息

Basson J J, Nel C J, De Wet J I, Monk E J

机构信息

Departement Chirurgie en Afdeling Biostatistiek, Universiteit van die Orange-Vrystaat, Bloemfontein.

出版信息

S Afr J Surg. 1992 Dec;30(4):145-7.

PMID:1295095
Abstract

The extent of reduction in cholesterol levels, the maintenance of low levels in the long-term, the morbidity and mortality as well as the acceptance of side-effects of the partial ileal bypass (PIB) is reviewed. The mean reduction in cholesterol levels following PIB was 35.2% in males and 35.8% in female patients. The reduction is significant and it is maintained over a 10-year period. The morbidity and mortality is low and side-effects are well tolerated. Our results indicate that the PIB may play an important role in the cholesterol-lowering armamentarium.

摘要

本文回顾了部分回肠旁路术(PIB)在降低胆固醇水平方面的效果、长期维持低胆固醇水平的情况、发病率和死亡率以及对副作用的接受程度。PIB术后男性患者胆固醇水平平均降低35.2%,女性患者降低35.8%。这种降低具有显著性,且在10年期间得以维持。发病率和死亡率较低,副作用耐受性良好。我们的结果表明,PIB可能在降胆固醇治疗手段中发挥重要作用。

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