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[部分回肠旁路术治疗家族性高胆固醇血症]

[The partial ileal bypass in the treatment of familial hypercholesterolemia].

作者信息

Lebedev L V, Sedletskiĭ Iu I, Mirchuk K K

出版信息

Vestn Khir Im I I Grek. 1993 May-Jun;150(5-6):30-3.

PMID:8091575
Abstract

Data on the influence of a partial ileal bypass on the level of lipids in 8 patients with a heterozygous variant of familial hypercholesterolemia are presented. The operation was followed by a decreased concentration of circulating cholesterol at the expense of cholesterol of low density lipoproteins, but the normalization of the lipid level in blood took place in 1 case only. To improve the results of treatment it is expedient to administer inhibitors of cholesterol synthesis in the postoperative period.

摘要

本文呈现了关于部分回肠旁路术对8例家族性高胆固醇血症杂合子变异患者血脂水平影响的数据。手术后,循环胆固醇浓度降低,是以低密度脂蛋白胆固醇为代价,但仅1例患者血液中的脂质水平恢复正常。为了改善治疗效果,在术后阶段给予胆固醇合成抑制剂是适宜的。

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