自动化固相碳水化合物合成的最新进展：从筛选到疫苗
Recent advances in automated solid-phase carbohydrate synthesis: from screening to vaccines.
作者信息
Plante Obadiah J, Seeberger Peter H
机构信息
Ancora Pharmaceuticals, 100 Cummings Center, Suite 419E, Beverly, MA 01915, USA.
出版信息
Curr Opin Drug Discov Devel. 2003 Jul;6(4):521-5.
PMID:12951815
Abstract
The past year has witnessed significant advances in a new technology for the synthesis of complex carbohydrates. Solid-phase methods have been applied to the construction of previously inaccessible carbohydrates. Furthermore, the application of automated solid-phase carbohydrate synthesis is promising. New methods for the synthesis of carbohydrates and potential applications are described in this review.
摘要
过去一年见证了复杂碳水化合物合成新技术的重大进展。固相方法已被应用于构建以前难以获得的碳水化合物。此外，自动化固相碳水化合物合成的应用前景广阔。本文综述了碳水化合物合成的新方法及其潜在应用。
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