Gerlai R
Saegis Pharmaceuticals, Inc., 60 Stone Pine Road, Suite 200, Half Moon Bay, CA 94019, USA.
Genes Brain Behav. 2003 Aug;2(4):187-8; discussion 189-90. doi: 10.1034/j.1601-183x.2003.00019.x.
In a recent article Rose (2002) raises numerous crucial issues with regard to the research into and the use of cognition or memory enhancing agents. Although development of 'smart' drugs is in its infancy, his paper delineates some issues society may have to face when these drugs arrive. Questions about the development of such drugs may be interesting to several readers of Genes Brain and Behavior given the wealth of information expected to be gained on brain function from studies using genetic approaches including mutagenesis, transgenic techniques and genomics in general. Besides the scientific questions, several ethical issues may need to be addressed that are of interest to us all. Rose (2002) discusses some of these questions, but perhaps presents a too negative view on the problems, especially with regard to the present and future of memory research. This paper is intended to focus mainly on the scientific questions and argues that our fear of complex ethical problems should not make us throw the baby (i.e., our research and discoveries) out with the bath water.
在最近的一篇文章中,罗斯(2002年)提出了许多关于认知或记忆增强剂的研究及应用的关键问题。尽管“智能”药物的研发尚处于起步阶段,但他的论文阐述了这些药物出现时社会可能不得不面对的一些问题。鉴于预计通过包括诱变、转基因技术以及一般基因组学在内的遗传方法研究能获取大量有关脑功能的信息,对于《基因、大脑与行为》的几位读者而言,此类药物的研发问题可能颇有趣味。除了科学问题外,还有几个伦理问题或许需要我们予以关注,这些问题是我们所有人都感兴趣的。罗斯(2002年)讨论了其中一些问题,但可能对这些问题呈现出过于消极的看法,尤其是在记忆研究的现状和未来方面。本文旨在主要聚焦科学问题,并认为我们对复杂伦理问题的担忧不应使我们因噎废食(即放弃我们的研究和发现)。