Styne Dennis M
Department of Pediatrics, University of California Davis Medical Center, Sacramento, CA 95817, USA.
Horm Res. 2003;60(Suppl 1):22-6. doi: 10.1159/000071222.
To understand the regulation of pubertal growth, it is important to understand the present concept of the control of the onset of puberty, the change in secretion of sex steroids during puberty, and the effects of these various factors upon the production and action of growth hormone (GH) and insulin-like growth factor (IGF). Nutrition plays a major role in this process because states of aberrant nutrition severely affect pubertal growth. In this article, all of these concepts will be discussed, including the effect of these factors upon bone growth during the increase in stature accomplished during puberty.
为了理解青春期生长的调节机制,了解当前关于青春期启动控制、青春期期间性类固醇分泌变化以及这些不同因素对生长激素(GH)和胰岛素样生长因子(IGF)的产生及作用的影响的概念非常重要。营养在这一过程中起着主要作用,因为营养异常状态会严重影响青春期生长。在本文中,将讨论所有这些概念,包括这些因素在青春期身高增长过程中对骨骼生长的影响。