Oligonucleotide fingerprinting in Xiphophorus melanoma. Detection of a melanoma associated DNA modification.
作者信息
Mäueler W, Schartl M, Epplen J T
机构信息
Ruhr-Universität, Bochum, Germany.
出版信息
J Exp Anim Sci. 1992 Dec;35(3):120-4.
PMID:1295577
Abstract
Oligonucleotide fingerprints have been generated from fish melanomas and were compared to the constitutional multilocus patterns from normal brain DNA of the same individual. In 3 out of 8 cases additional bands were observed in the tumor DNA. This phenomenon can only be explained satisfactorily by so far unknown modes of DNA modification.
摘要
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