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Oligonucleotide fingerprinting in Xiphophorus melanoma. Detection of a melanoma associated DNA modification.

作者信息

Mäueler W, Schartl M, Epplen J T

机构信息

Ruhr-Universität, Bochum, Germany.

出版信息

J Exp Anim Sci. 1992 Dec;35(3):120-4.

PMID:1295577
Abstract

Oligonucleotide fingerprints have been generated from fish melanomas and were compared to the constitutional multilocus patterns from normal brain DNA of the same individual. In 3 out of 8 cases additional bands were observed in the tumor DNA. This phenomenon can only be explained satisfactorily by so far unknown modes of DNA modification.

摘要

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