Wei D, Yuan W, Yin G, Yuan Z, Chen M
East China University of Chemical Technology, Shanghai.
Chin J Biotechnol. 1992;8(3):195-201.
This paper aims at analyzing the bioconversion process from L-sorbose to 2-Keto-L-gulonic acid with the aid of the growth factor assumption. Fermentation mechanism is discussed after making necessary simplifications. A model is established for this second step fermentation process. Nonlinear optimization together with Runge-Kutta method, are used to obtain model parameters. Results of computer simulation agree with experimental data to show the reliability of the kinetic model.
本文旨在借助生长因子假设分析从L-山梨糖到2-酮基-L-古龙酸的生物转化过程。在进行必要简化后讨论了发酵机制。为该第二步发酵过程建立了一个模型。使用非线性优化方法结合龙格-库塔方法来获取模型参数。计算机模拟结果与实验数据相符，表明了动力学模型的可靠性。
