Eisele David W, Schwartz Alan R, Smith Philip L
Department of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, 400 Parnassus Avenue, Suite A-730, San Francisco, CA 94143-0342, USA.
Otolaryngol Clin North Am. 2003 Jun;36(3):501-10. doi: 10.1016/s0030-6665(02)00178-0.
Recent studies have shown that neuromuscular stimulation of the genioglossus muscle and direct stimulation of the hypoglossal nerve can be performed selectively and safely. Such stimulation, delivered below the arousal threshold, can modulate airflow during sleep in patients with OSA. The feasibility and potential of upper airway stimulation for the treatment of OSA have been demonstrated. Further studies and stimulation-system refinements are presently underway, with hopes of establishing upper airway stimulation as a therapeutic option for this challenging disorder.
最近的研究表明，对颏舌肌进行神经肌肉刺激以及直接刺激舌下神经可以选择性且安全地进行。这种在觉醒阈值以下进行的刺激，可以调节阻塞性睡眠呼吸暂停（OSA）患者睡眠期间的气流。上气道刺激治疗OSA的可行性和潜力已得到证实。目前正在进行进一步的研究和刺激系统的改进，希望将上气道刺激确立为这种具有挑战性疾病的一种治疗选择。
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