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孟鲁司特相关的变应性肉芽肿性血管炎

Montelukast-associated Churg-Strauss syndrome.

作者信息

Michael Atef B, Murphy David

机构信息

Birmingham Heartlands Hospital, Bordsley Green, Birmingham B9 5SS, UK.

出版信息

Age Ageing. 2003 Sep;32(5):551-2. doi: 10.1093/ageing/afg076.

Abstract

A 68-year-old asthmatic presented markedly unwell with arthralgia, mononeuritis multiplex, peripheral neuropathy, and eosinophilia. His past medical history included perennial rhinitis, and nasal polyps. Three months prior to admission his prednisolone was stopped and Montelukast was started. The diagnosis of Montelukast-associated Churg-Strauss syndrome was made. The drug was stopped and steroids started with general improvement and reduction of eosinophilia; however, the neurological deficit persisted.

摘要

一名68岁的哮喘患者出现明显不适,伴有关节痛、多发性单神经炎、周围神经病变和嗜酸性粒细胞增多。他既往有常年性鼻炎和鼻息肉病史。入院前三个月,他停用了泼尼松龙并开始服用孟鲁司特。诊断为孟鲁司特相关的Churg-Strauss综合征。停用该药物并开始使用类固醇,患者总体情况改善,嗜酸性粒细胞增多减轻;然而,神经功能缺损持续存在。

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