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孟鲁司特相关的变应性肉芽肿性血管炎

Montelukast-associated Churg-Strauss syndrome.

作者信息

Michael Atef B, Murphy David

机构信息

Birmingham Heartlands Hospital, Bordsley Green, Birmingham B9 5SS, UK.

出版信息

Age Ageing. 2003 Sep;32(5):551-2. doi: 10.1093/ageing/afg076.

DOI:10.1093/ageing/afg076
PMID:12958007
Abstract

A 68-year-old asthmatic presented markedly unwell with arthralgia, mononeuritis multiplex, peripheral neuropathy, and eosinophilia. His past medical history included perennial rhinitis, and nasal polyps. Three months prior to admission his prednisolone was stopped and Montelukast was started. The diagnosis of Montelukast-associated Churg-Strauss syndrome was made. The drug was stopped and steroids started with general improvement and reduction of eosinophilia; however, the neurological deficit persisted.

摘要

一名68岁的哮喘患者出现明显不适,伴有关节痛、多发性单神经炎、周围神经病变和嗜酸性粒细胞增多。他既往有常年性鼻炎和鼻息肉病史。入院前三个月,他停用了泼尼松龙并开始服用孟鲁司特。诊断为孟鲁司特相关的Churg-Strauss综合征。停用该药物并开始使用类固醇,患者总体情况改善,嗜酸性粒细胞增多减轻;然而,神经功能缺损持续存在。

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引用本文的文献

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EOSINOPHILIC GRANULOMATOSIS WITH POLYANGIITIS INDUCED BY MONTELUKAST.孟鲁司特诱发的嗜酸性肉芽肿性多血管炎
Acta Clin Croat. 2024 Apr;63(1):45-54. doi: 10.20471/acc.2024.63.01.6.
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Eosinophilic granulomatosis with polyangiitis and its association with montelukast: a case-based review.嗜酸性肉芽肿性多血管炎及其与孟鲁司特的关联:基于病例的综述
Clin Rheumatol. 2024 Jun;43(6):2153-2165. doi: 10.1007/s10067-024-07000-8. Epub 2024 May 8.
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Leukotriene Antagonists in Dermatology.皮肤科中的白三烯拮抗剂
Indian J Dermatol. 2021 Sep-Oct;66(5):575. doi: 10.4103/ijd.IJD_557_18.
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A case of montelukast-induced churg-strauss syndrome associated with liver dysfunction.一例与肝功能障碍相关的孟鲁司特诱发的变应性肉芽肿性血管炎。
Case Reports Hepatol. 2011;2011:412524. doi: 10.1155/2011/412524. Epub 2011 Jul 9.
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Churg-strauss syndrome in the pediatric age group.儿童期变应性肉芽肿性血管炎。
World Allergy Organ J. 2008 Feb;1(2):34-40. doi: 10.1097/WOX.0b013e3181626fde.
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The linkage between Churg-Strauss syndrome and leukotriene receptor antagonists: fact or fiction?Churg-Strauss 综合征与白三烯受体拮抗剂的关联:事实还是虚构?
Ther Clin Risk Manag. 2005 Jun;1(2):125-40. doi: 10.2147/tcrm.1.2.125.62913.
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Montelukast in the treatment of allergic rhinitis: an evidence-based review.孟鲁司特治疗变应性鼻炎:一项循证综述
Drugs. 2007;67(6):887-901. doi: 10.2165/00003495-200767060-00005.