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评估荟萃分析中的异质性

Measuring inconsistency in meta-analyses.

作者信息

Higgins Julian P T, Thompson Simon G, Deeks Jonathan J, Altman Douglas G

机构信息

MRC Biostatistics Unit, Institute of Public Health, Cambridge CB2 2SR.

出版信息

BMJ. 2003 Sep 6;327(7414):557-60. doi: 10.1136/bmj.327.7414.557.

DOI:10.1136/bmj.327.7414.557
PMID:12958120
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC192859/
Abstract

Cochrane Reviews have recently started including the quantity to help readers assess the consistency of the results of studies in meta-analyses. What does this new quantity mean, and why is assessment of heterogeneity so important to clinical practice?

摘要

Cochrane系统评价最近开始纳入这一指标，以帮助读者评估Meta分析中各研究结果的一致性。这个新指标是什么意思，以及异质性评估为何对临床实践如此重要？

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本文引用的文献

[1]
WITHDRAWN: Treatment discontinuation with selective serotonin reuptake inhibitors (SSRIs) versus tricyclic antidepressants (TCAs).

Cochrane Database Syst Rev. 2007-7-18

[2]
Amantadine and rimantadine for preventing and treating influenza A in adults.

Cochrane Database Syst Rev. 2002

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Stat Med. 2002-6-15

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Stat Med. 2002-6-15

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J Health Serv Res Policy. 2002-1

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Stat Med. 2001-12-15

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J Clin Epidemiol. 2001-10

[8]
A new system for grading recommendations in evidence based guidelines.

BMJ. 2001-8-11

[9]
Which guidelines can we trust?: Assessing strength of evidence behind recommendations for clinical practice.

West J Med. 2001-4

[10]
Heterogeneity and statistical significance in meta-analysis: an empirical study of 125 meta-analyses.

Stat Med. 2000-7-15

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