Fernández Pérez Cristina, Barreales Tolosa Laura, Coll Torres Elisabeth, Tejada Cazorla Juan
Servicio de Medicina Preventiva Planta 4a norte Hospital Clínico San Carlos C/Profesor Martín Lagos s/n 28040 Madrid, España.
Arch Esp Urol. 2003 Jul-Aug;56(6):595-604.
The use of statistics in medical articles has risen a lot during the last decades, however it is used in a thoughtless manner in many instances. Today, Statistics is the only tool that allows the medical researcher to obtain results and benefits from those studies the relationships of which can not be interpreted from a determinist perspective, because it is a branch of applied mathematics objective of which is to manage and quantify the uncertainty of the available information, to support decision taking. The objective of this article is to review the basic statistical concepts that every doctor should know to be able to perform and/or detect quality research, as well as to underline the most frequent errors committed when interpreting statistical results. We review the general concepts about data synthesis and differentiation of the different types of measurements, hypothesis testing and errors that can be committed doing it, the real meaning of the "p" value, differentiation between statistically significant and clinically relevant results, the importance of confidence intervals as a measure of significance and clinical relevance, the confusion generated between two concepts that are different as standard deviation and standard error, and the criteria that govern the selection of the adequate statistical tests to evaluate relationships between variables.
在过去几十年中,医学文章中统计数据的使用大幅增加,然而在许多情况下,其使用方式却缺乏思考。如今,统计学是唯一能让医学研究人员从那些无法从决定论角度解释其关系的研究中获得结果和益处的工具,因为它是应用数学的一个分支,其目标是管理和量化现有信息的不确定性,以支持决策制定。本文的目的是回顾每个医生为了能够进行和/或检测高质量研究而应了解的基本统计概念,同时强调在解释统计结果时最常犯的错误。我们回顾了关于数据综合以及不同类型测量的区分、假设检验和进行假设检验时可能犯的错误、“p”值的实际意义、统计学显著结果与临床相关结果之间的区别、作为显著性和临床相关性度量的置信区间的重要性、标准差和标准误差这两个不同概念之间产生的混淆,以及指导选择适当统计检验以评估变量之间关系的标准。