Sashiwa Hitoshi, Yamamori Naoki, Ichinose Yoshifumi, Sunamoto Junzo, Aiba Sei-ichi
Green Biotechnology RG, The Special Division for Human Life Technology, AIST Kansai, 1-8-31 Midorigaoka, Ikeda 563-8577 Japan.
Biomacromolecules. 2003 Sep-Oct;4(5):1250-4. doi: 10.1021/bm030022o.
A Michael reaction of chitosan was conducted in water containing acetic acid with various acryl reagents. The degree of substitution could be controlled by temperature, reaction time, and the amount of acryl reagents. Although the modified chitosan derivatives with acrylic acid esters showed water-solubility, that with poly(ethylene glycol) acrylate, however, turned to water-insoluble material by lyophilization. Good biodegradation was observed in modified chitosan derivatives by standard activated sludge.
在含有乙酸的水中，壳聚糖与各种丙烯酸试剂进行迈克尔反应。取代度可通过温度、反应时间和丙烯酸试剂的用量来控制。虽然含丙烯酸酯的改性壳聚糖衍生物表现出水溶性，但含聚乙二醇丙烯酸酯的改性壳聚糖衍生物经冻干后变成了水不溶性材料。通过标准活性污泥观察到改性壳聚糖衍生物具有良好的生物降解性。
