Leicher H
Laryngol Rhinol Otol (Stuttg). 1975 Apr;54(4):279-90.
A multiple stimulus (secondary or repetitive stimulus) to the sensory nerve endings in the skin and in the connective subcutaneous tissue is exerted by acupuncture. Because of the tight interlacing of nerve endings, this stimulus affects simultaneously the sensory fibres of both the cerebrospinal nerve, the Sympathicus and the Parasympathicus. The slow conducting pain fibres (C-fibres) are inhibited in their function by the fast conducting Abeta-fibres and Adelta-fibres, which transmit pressure, vibration and electric currents (Foerster, Zottermann). In addition a secondary stimulus inhibits or modulates a peripheral pain stimulus (pain of operation) in various synapses on the sensory pathway to the cortex, especially in the substantia gelatinosa of the spinal cord. According to Keidel, Raich and Albrecht pain stimuli are masked up to 50% by vibration and other "rivaling" stimuli. Furthermore, acupuncture releases a higher level of Noradrenaline and Serotonine in the liquor of ventricles. These two biogenic amines effect also an analgesia such as demonstrated in animals by artificial injection in the ventricles. The author gives also a detailed review about the importance of the transmitters noradrenaline, serotonine and acteylcholine for the acupuntural analgesia.
针刺对皮肤和皮下结缔组织中的感觉神经末梢施加多重刺激(二次或重复刺激)。由于神经末梢紧密交织,这种刺激会同时影响脑脊神经、交感神经和副交感神经的感觉纤维。传导速度慢的痛觉纤维(C纤维)的功能会受到传导速度快的Aβ纤维和Aδ纤维的抑制,后者传导压力、振动和电流(福斯特、措特曼)。此外,二次刺激会在通往皮层的感觉通路上的各种突触中,尤其是在脊髓的胶状质中,抑制或调节外周疼痛刺激(手术疼痛)。根据凯德尔、赖希和阿尔布雷希特的研究,振动和其他“竞争”刺激可使疼痛刺激被掩盖高达50%。此外,针刺会使脑室液中的去甲肾上腺素和血清素水平升高。这两种生物胺也会产生镇痛作用,就像在动物脑室中人工注射所证明的那样。作者还详细回顾了神经递质去甲肾上腺素、血清素和乙酰胆碱对针刺镇痛的重要性。