Lange Aksel, Funch-Jensen Peter, Schiøtz Peter Oluf
Department of Pediatrics, Aarhus University Hospital, Denmark.
J Pediatr Gastroenterol Nutr. 2003 Sep;37(3):294-9. doi: 10.1097/00005176-200309000-00017.
Gastrointestinal symptoms have been reported in association with myoelectrical dysrhythmia, where different types of gastric electrical activity have been described. These types of gastric myoelectrical activity and dysrhythmia can be measured by electrogastrography using cutaneous electrodes. Epigastric impedance is a non-invasive method used to study gastric emptying time and gastric phasic activity. At present no study of gastric dysrhythmia, measured with epigastric impedance, has been presented, and the purpose of the present study was to investigate gastric rhythms by means of impedance gastrography in control infants, compared to infants with different gastrointestinal diseases, before and after treatment of their disease.
21 patients (age 0-2 months) and 40 healthy infants (age 0-2 months) were investigated. The patients suffered from partial or total intestinal obstruction, necrotizing enterocolitis or pyloric stenosis.All infants were fasting and studied during periods of at least one hour. The patients were examined in the acute state and after treatment when possible.
A pathologic result was found in 90% of the patients. A persistent phasic activity pattern was found in 19 of the 21 patients, high frequency phasic activity in 11 of the 21 patients. Short-term phasic activity was only found in 13 out of 40 of the normal infants (32.5%).
Using epigastric impedance we found that infants with partial or total intestinal obstruction had gastric phasic activity, which was not found in the control infants. The origin of the gastric phasic activity patterns is unknown, but they may be related to electrical control activity.
已有报道称胃肠症状与肌电节律失常有关，其中描述了不同类型的胃电活动。这些类型的胃肌电活动和节律失常可通过使用皮肤电极的胃电图进行测量。上腹部阻抗是一种用于研究胃排空时间和胃相活动的非侵入性方法。目前尚未有使用上腹部阻抗测量胃节律失常的研究，本研究的目的是通过阻抗胃电图研究对照婴儿以及患有不同胃肠疾病的婴儿在疾病治疗前后的胃节律。
对21例患者（年龄0 - 2个月）和40例健康婴儿（年龄0 - 2个月）进行了研究。患者患有部分或完全肠梗阻、坏死性小肠结肠炎或幽门狭窄。所有婴儿均禁食，并在至少一小时的时间段内进行研究。患者在急性期和可能的治疗后进行检查。
90%的患者出现病理结果。21例患者中有19例出现持续的相活动模式，21例患者中有11例出现高频相活动。在40例正常婴儿中，只有13例（32.5%）出现短期相活动。
通过上腹部阻抗，我们发现部分或完全肠梗阻的婴儿存在胃相活动，而对照婴儿中未发现这种情况。胃相活动模式的起源尚不清楚，但它们可能与电控制活动有关。
