Salwa-Zurawska W, Bortkiewicz E, Turczuk-Bierła I, Maciejewski J
Department of Clinical Pathomorphology, Marcinkowski School of Medicine, Poznań.
Patol Pol. 1992;43(2):45-50.
Clinical and morphological examinations in 25 children with the diagnosis of focal segmental glomerulosclerosis (FSG) show that: 1. electron microscopy permits a detection of FSG in its early stage when light microscopy does not reveal any changes, and immunomorphological studies do not show deposits 2. in this stage small focal interstitial changes may be visible 3. ultrastructural studies reveal changes in case of nonspecific light microscopy i.e. suggesting mesangial glomerulonephritis 4. in doubtful cases it is useful to repeat biopsy.
对25例诊断为局灶节段性肾小球硬化（FSG）的儿童进行的临床和形态学检查表明：1. 电子显微镜检查能够在光镜未发现任何变化且免疫形态学研究未显示沉积物时检测到FSG的早期阶段；2. 在这个阶段可能会出现小的局灶性间质变化；3. 超微结构研究揭示了非特异性光镜检查情况下的变化，即提示系膜增生性肾小球肾炎；4. 在可疑病例中，重复活检是有用的。
