Roblin D Graham, Eccles Ronald
Common Cold Center Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3US, United Kingdom.
Am J Rhinol. 2003 Jul-Aug;17(4):179-83.
Nasal spirometry has been used previously to monitor the nasal cycle. Asymmetry of nasal airflow is expressed as a nasal partitioning ratio (NPR) that ranges from -1 (left nasal cavity obstruction) to + (right nasal cavity obstruction) with 0 indicating symmetry of airflow. This study investigated the normal range of NPR in the decongested nose as a means of assessing the degree of nasal septal deviation.
NPR was measured in 100 healthy volunteers using a portable spirometer.
Mean NPR before decongestion was -0.1 +/- 0.32 SD (range, -0.84-0.75), and after decongestion mean NPR was -0.02 +/- 0.16 SD (range, -0.46-0.51). Male NPR ranged from -0.46 to 0.51 (mean, -0.1 +/- 0.22) whereas female NPR was from -0.21 to 0.37 (mean, -0.03 +/- 0.1; p < 0.001). There was a significant correlation between the clinicians assessment of the degree of septal deviation and NPR, r(s) = 0.69 (p < 0.01). The 95% reference range for NPR in this normal population was found to be between +0.30 and -0.34.
A normal range of NPR may prove useful in assessing patients complaining of nasal obstruction. A case may be made that patients on the waiting list that fall within the normal range of NPR are unlikely to benefit from septal surgery because their nasal passages are not greatly asymmetrical.
鼻肺量计先前已用于监测鼻周期。鼻气流不对称表现为鼻部分配比（NPR），范围从-1（左鼻腔阻塞）到+1（右鼻腔阻塞），0表示气流对称。本研究调查了鼻充血缓解后NPR的正常范围，以此作为评估鼻中隔偏曲程度的一种方法。
使用便携式肺量计对100名健康志愿者测量NPR。
充血前平均NPR为-0.1±0.32标准差（范围，-0.84至0.75），充血后平均NPR为-0.02±0.16标准差（范围，-0.46至0.51）。男性NPR范围为-0.46至0.51（平均，-0.1±0.22），而女性NPR为-0.21至0.37（平均，-0.03±0.1；p<0.001）。临床医生对鼻中隔偏曲程度的评估与NPR之间存在显著相关性，r(s)=0.69（p<0.01）。该正常人群中NPR的95%参考范围为+0.30至-0.34。
NPR的正常范围可能有助于评估主诉鼻塞的患者。可以认为，等候名单上NPR在正常范围内的患者不太可能从鼻中隔手术中获益，因为他们的鼻腔通道并非严重不对称。
