Passos Carlos José, Mergler Donna, Gaspar Elizete, Morais Silmara, Lucotte Marc, Larribe Fabrice, Davidson Robert, de Grosbois Sylvie
Centre d'études des interactions biologiques entre la santé et l'environnement (CINBIOSE), Université du Québec à Montréal, CP 8888, Succ Centre-ville, Montréal, Canada H3P 3P8.
Environ Res. 2003 Oct;93(2):123-30. doi: 10.1016/s0013-9351(03)00019-7.
This study aimed to examine the influence of the consumption of traditional foods on the relationship between fish consumption and mercury (Hg) exposure. A 12-month prospective dietary survey was carried out with 26 adult women from a fish-eating community in the Brazilian Amazon. Food ingestion was determined using a daily food diary, and total hair Hg levels were assessed for each month through sequential analyses using cold vapor atomic absorption spectrometry. Simple and multiple regression analyses showed that the strong relationship between fish consumption and Hg exposure was significantly modified by fruit consumption: for the same number of fish meals, those who ate more tropical fruits had lower hair mercury levels. The findings of this study indicate different ways of maintaining fish consumption while reducing Hg exposure in the Amazon. A number of phytochemicals and nutritional fibers present in fruits might be interacting with Hg in several ways: absorption and excretion, transport, binding to target proteins, metabolism, and sequestration. More studies are required on larger populations to further elucidate the extent and public health implications of the use of fruits to counteract the toxic action of methylmercury.
本研究旨在探讨传统食物的消费对鱼类消费与汞(Hg)暴露之间关系的影响。对来自巴西亚马逊地区一个食鱼社区的26名成年女性进行了为期12个月的前瞻性饮食调查。通过每日饮食日记确定食物摄入量,并使用冷蒸气原子吸收光谱法通过顺序分析评估每个月的头发总汞水平。简单和多元回归分析表明,水果消费显著改变了鱼类消费与汞暴露之间的强关系:对于相同数量的鱼餐,食用更多热带水果的人头发汞水平较低。本研究结果表明了在亚马逊地区维持鱼类消费同时减少汞暴露的不同方法。水果中存在的多种植物化学物质和营养纤维可能通过多种方式与汞相互作用:吸收与排泄、运输、与靶蛋白结合、代谢和螯合。需要对更多人群进行进一步研究,以进一步阐明使用水果抵消甲基汞毒性作用的程度及其对公共卫生的影响。