Curtis Clayton E., D'Esposito Mark
New York University, Department of Psychology, 6 Washington Place, Room 859, 10003, New York, NY, USA
Trends Cogn Sci. 2003 Sep;7(9):415-423. doi: 10.1016/s1364-6613(03)00197-9.
The dorsolateral prefrontal cortex (DLPFC) plays a crucial role in working memory. Notably, persistent activity in the DLPFC is often observed during the retention interval of delayed response tasks. The code carried by the persistent activity remains unclear, however. We critically evaluate how well recent findings from functional magnetic resonance imaging studies are compatible with current models of the role of the DLFPC in working memory. These new findings suggest that the DLPFC aids in the maintenance of information by directing attention to internal representations of sensory stimuli and motor plans that are stored in more posterior regions.
背外侧前额叶皮层（DLPFC）在工作记忆中起着至关重要的作用。值得注意的是，在延迟反应任务的保持间隔期间，经常会观察到DLPFC中的持续性活动。然而，这种持续性活动所携带的编码仍不清楚。我们批判性地评估了功能磁共振成像研究的最新发现与当前DLFPC在工作记忆中作用模型的契合程度。这些新发现表明，DLPFC通过将注意力导向存储在更靠后区域的感觉刺激和运动计划的内部表征，来帮助维持信息。
