天然产物——解释化学多样性的一个简单模型。
Natural products--a simple model to explain chemical diversity.
作者信息
Firn Richard D, Jones Clive G
机构信息
Department of Biology, University of York, UK.
出版信息
Nat Prod Rep. 2003 Aug;20(4):382-91. doi: 10.1039/b208815k.
DOI:10.1039/b208815k
PMID:12964834
Abstract
A simple evolutionary model is presented which explains why organisms produce so many natural products, why so many have low biological activity, why enzymes involved in natural product synthesis have the properties they do and why natural product metabolism is shaped as it is.
摘要
提出了一个简单的进化模型，该模型解释了生物体为何产生如此多的天然产物，为何如此多的天然产物具有低生物活性，参与天然产物合成的酶为何具有它们所具有的特性，以及天然产物代谢为何是现在这样的形态。
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