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[促黄体激素对炎症灶中细胞和血管反应的影响]

[Modification of the cellular and vascular reactions in the inflammatory focus by luteotropic hormone].

作者信息

Vasil'eva L S, Kuz'menko V V, Malyshev V V

出版信息

Arkh Patol. 1992;54(12):5-8.

PMID:1296569
Abstract

Luteotropic hormone considerably alters the dynamics of experimental inflammation. A decrease of microvascular bed activation and the density of macrophage population are observed at early stages of the inflammation. Inhibition of fibroblast proliferative activity and acceleration of their differentiation are revealed during the period of reparation. The formation of the capsule went more intensely, but collagen synthesis was inhibited and fibrous tissue formed more slowly. The results obtained prove principal possibility of inflammation regulation by means of mediators and metabolites of the stress-limiting systems.

摘要

促黄体生成素可显著改变实验性炎症的动态过程。在炎症早期可观察到微血管床激活减少以及巨噬细胞群体密度降低。在修复期发现成纤维细胞增殖活性受到抑制,其分化加速。包膜形成更为强烈,但胶原蛋白合成受到抑制,纤维组织形成更缓慢。所获得的结果证明了通过应激限制系统的介质和代谢产物调节炎症的主要可能性。

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