Joss A W, Davidson M M, Ho-Yen D O, Ludbrook A
Department of Microbiology, Raigmore Hospital, Inverness IV2 3UJ, UK.
Public Health. 2003 Jul;117(4):264-73. doi: 10.1016/S0033-3506(03)00067-2.
This paper analyses likely Lyme disease costs incurred by patients tested in the authors' laboratory over an 18 month period, based on patient histories and test results relating to 2110 samples submitted from laboratories serving 59% of the Scottish population. Cost analysis takes account of the direct costs of consultation, laboratory tests, antibiotic treatment and management of any sequelae, as well as indirect costs of the loss of healthy time through illness. Standard costs for each element are derived from published information, and the proportions applied to each patient category are estimated from studies described elsewhere in the literature. Of the sample, 295 patients had evidence of early Lyme disease and 31 had late Lyme disease symptoms. Based on these figures, the total annual cost for Lyme disease, when projected to the whole of Scotland, is estimated to be significant at 331,000 Pounds (range 47,000-615,000 Pounds). The range is inevitably wide because it was not possible to document complete clinical and management histories on individual patients. In addition, some late Lyme disease sequelae will require management for more than 1 year, and costs are also identified that could justifiably be included for all the other patients who tested negative for Lyme disease. These data raise the question of whether there is sufficient focus on prevention and the best management of this disease.
本文根据为占苏格兰人口59%的实验室提交的2110份样本的患者病史和检测结果,分析了在作者实验室接受检测的患者在18个月期间可能产生的莱姆病费用。成本分析考虑了咨询、实验室检测、抗生素治疗和任何后遗症管理的直接成本,以及因疾病导致健康时间损失的间接成本。每个要素的标准成本来自已发表的信息,应用于每个患者类别的比例是根据文献其他地方描述的研究估计的。在样本中,295名患者有早期莱姆病的证据,31名有晚期莱姆病症状。根据这些数字,当推算到整个苏格兰时,莱姆病的年度总成本估计为33.1万英镑(范围为4.7万-61.5万英镑),这一数字相当可观。由于无法记录每个患者完整的临床和管理病史,这个范围不可避免地很宽。此外,一些晚期莱姆病后遗症需要治疗一年以上,并且还确定了一些成本,这些成本理应包含在所有莱姆病检测呈阴性的其他患者身上。这些数据引发了一个问题,即对于这种疾病的预防和最佳管理是否给予了足够的关注。