University of Maryland School of Pharmacy, Baltimore, Maryland, USA.
University of Maryland Institute of Human Virology, Baltimore, Maryland, USA.
Parasit Vectors. 2020 Jul 9;13(1):341. doi: 10.1186/s13071-020-04214-y.
The financial implications of Lyme disease (LD) can vary widely for both the health system and the individual patients experiencing the disease. The aim of this review was to summarize published data on clinical and economic outcomes associated with LD.
A literature review was conducted to identify all studies of LD that incorporate both clinical outcomes and costs. Included studies were described and categorized based on costs consistent with best practices used in economic evaluation.
The most frequent costs identified focused on formal health costs and productivity losses were the most common costs identified outside of the health system. Travel and informal care costs were less frequently reported. Clinical and economic outcomes of LD are primarily studied through economic models or observational analyses and focus on formal health care.
This review provides and overview of existing evidence and recommendations for future economic analyses in LD.
莱姆病（LD）对卫生系统和患有该病的个体患者的财务影响可能差异很大。本综述的目的是总结与 LD 相关的临床和经济结果的已发表数据。
进行文献综述，以确定所有纳入临床结果和成本的 LD 研究。根据经济评估中使用的最佳实践，对纳入的研究进行描述和分类。
确定的最常见成本主要集中在正规医疗费用上，而在卫生系统之外，最常见的成本是生产力损失。旅行和非正式护理成本的报告较少。LD 的临床和经济结果主要通过经济模型或观察性分析进行研究，重点是正规医疗保健。
本综述提供了 LD 现有证据的概述，并为未来的经济分析提出了建议。
