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[显微外科淋巴管移植]

[The microsurgical lymph vessel transplantation].

作者信息

Baumeister R G H, Frick A

机构信息

Plastische, Hand-, Mikrochirurgie, Chirurgische Klinik und Poliklinik - Grosshadern, Klinikum der Universität München, Germany.

出版信息

Handchir Mikrochir Plast Chir. 2003 Jul;35(4):202-9. doi: 10.1055/s-2003-42131.

DOI:10.1055/s-2003-42131
PMID:12968216
Abstract

Using advanced microsurgical techniques, single lymph vessels can be safely anastomosed and segments of lymphatics can bridge localized lymphatic blockades which are mostly due to lymphadenectomies. Lymphatic grafts are harvested from the patient's thigh with a length up to about 30 cm. In the case of an axillary blockade they are anastomosed with ascending lymph vessels at the upper arm and lymph vessels at the supraclavicular region. Unilateral oedemas of lower extremities are treated by transferring the grafts via the symphysis and anastomosing them with ascending lymphatics at the affected side. Lymphoedemas of the penis and the scrotum as well as lymphoedemas due to a localized peripheral lymphatic blockade can be treated by lymphatic grafts. In 127 arm oedemas the original difference in volume between the affected and the healthy arm was reduced at two third from 3368 cm (3) to 2567 cm(3) (p < 0.001). After a follow-up period of 2.6 years the volume was reduced to 2625 cm(3) (p < 0.001). The group of patients with a follow-up of at least ten years showed a volume of 2273 cm(3) (p < 0.001). The volume of unilateral lower extremity-lymphoedemas was reduced from 13 098 cm(3) to 10 578 cm(3) (p < 0.001) and showed a volume of 11 074 cm(3) after 1.7 years (p < 0.001) and 10 692 cm(3) after four years (p < 0.001). The original mean volume of the healthy contralateral leg was 9371 cm(3). Bridging localized gaps in the lymphatic system by autologous lymphatic grafts showed long lasting stable results. Starting the treatment of lymphoedemas by conservative procedures, one should not wait too long to ascertain the possibility of a microsurgical reconstruction in order to avoid increasing secondary tissue changes.

摘要

运用先进的显微外科技术,可安全地吻合单条淋巴管,且淋巴管段能够跨越局部淋巴管阻塞,这种阻塞大多是由淋巴结切除术所致。淋巴管移植物取自患者大腿,长度可达约30厘米。对于腋窝阻塞的情况,将其与上臂的上行淋巴管以及锁骨上区域的淋巴管进行吻合。下肢单侧水肿通过经耻骨联合转移移植物并将其与患侧的上行淋巴管吻合来治疗。阴茎和阴囊的淋巴水肿以及局部外周淋巴管阻塞引起的淋巴水肿可用淋巴管移植物治疗。在127例手臂水肿中,患侧与健侧手臂最初的体积差异从3368立方厘米减少了三分之二,降至2567立方厘米(p<0.001)。经过2.6年的随访期后,体积降至2625立方厘米(p<0.001)。随访至少十年的患者组体积为2273立方厘米(p<0.001)。单侧下肢淋巴水肿的体积从13098立方厘米降至10578立方厘米(p<0.001),1.7年后体积为11074立方厘米(p<0.001),四年后为10692立方厘米(p<0.001)。对侧健康腿的原始平均体积为9371立方厘米。通过自体淋巴管移植物弥合淋巴系统中的局部间隙显示出长期稳定的效果。采用保守程序开始治疗淋巴水肿时,不应等待过长时间来确定显微外科重建的可能性,以免增加继发性组织变化。

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Supermicrosurgical lymphaticovenular anastomosis and lymphaticovenous implantation for treatment of unilateral lower extremity lymphedema.超显微淋巴管静脉吻合术和淋巴管静脉植入术治疗单侧下肢淋巴水肿。
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