Bychkova E Iu, Krotov V P, Moleva E B, Medvedev O S
Aviakosm Ekolog Med. 1992 Jul-Aug;26(4):60-4.
The male Wistar rats were used to study an effect of preliminary antiorthostatic training on the systemic and regional hemodynamics during 24-hour head down tilting (HDT). It is indicated that the main parameters of the systemic hemodynamics (arterial blood pressure, heart rate, central venous pressure, total peripheric resistance, systemic veins) in trained animals were changed to a lesser extent as opposed to the controls. The dynamics of the mean pressure of blood filling--a parameter responsible for the state of systemic veins of the body--was group different. The blood flow changes in the organs and tissues were tended to be the same, however these changes were less severe in the trained rats. Thus pretraining of the rats, not changing the general trend of the shifts in the recorded values, decreases the severity of their variations.