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[头低位倾斜低动力与γ射线照射对大鼠高级神经活动的联合作用]

[The combined action of head-down tilt hypodynamia and gamma irradiation on higher nervous activity in rats].

作者信息

Shtemberg A S

出版信息

Aviakosm Ekolog Med. 1992 Jul-Aug;26(4):64-7.

PMID:1296844
Abstract

The paper deals with a combined effect of 30-day HDT and gamma radiation at a dose of 3 Gy on the higher nervous activity of the experimental rats. In the rats, the immobilization and isolation stresses induced by HDT are found to cause the development of pathologic aggressive reaction with the disorder of a species-typical pattern of an aggressive act and long-term change in animal social relations. The 30-day HDT disturbs the process of forming the motor-drinking differentiated conditioned reflex coming to a reduction of internal inhibition, generalization and sluggishness of a stimulation process. Functionally, these processes are reflected by a behavioral pattern shifting to stable stereotype impeding the formation of differentiated inhibition. Against HDT the unidirectional gamma radiation exposure increases this effect. In some cases, it leads to blocking the adaptational processes showing in the development of neurotic responses or deep, beyond the limits, inhibition.

摘要

本文探讨了30天卧床休息(HDT)与3 Gy剂量的γ辐射对实验大鼠高级神经活动的联合影响。研究发现,HDT诱导的固定和隔离应激会导致大鼠出现病理性攻击反应,攻击行为的物种典型模式紊乱,动物社会关系发生长期变化。30天的HDT会干扰运动-饮水分化条件反射的形成过程,导致内抑制减弱、刺激过程泛化和迟缓。在功能上,这些过程表现为行为模式转变为稳定的刻板行为,阻碍分化抑制的形成。与HDT相反,单向γ辐射暴露会增强这种效应。在某些情况下,会导致适应性过程受阻,表现为神经症反应的发展或深度抑制,超出正常范围。

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Aviakosm Ekolog Med. 1992 Jul-Aug;26(4):64-7.
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