Osadchiĭ L I, Balueva T V, Sergeev I V
I. P. Pavlov Institute of Physiology, Russian Acad. Sci., 199034, St. Petersburg, Nab. Makarova, 6, Russia.
Ross Fiziol Zh Im I M Sechenova. 2003 Mar;89(3):339-46.
In anaesthetised rats, bending of the body for 30 degrees and 45 degrees entailed a reverse linear dependence between the systolic and diastolic pressures under conditions of initial blood pressure over 95 mm Hg, whereas in initial blood pressure lower than 95 mm Hg the dependence is direct. In bending of the body for 60 degrees the dependence was direct and only present in initial blood pressure lower than 95 mm Hg. Pressor effects of mesaton in orthostasis directly depended on the level of the initial blood pressure. Any dependence of the cardiac output shifts on the initial blood pressure was absent. The direction and the degree of the arterial system reactivity's changes in response to orthostasis and adrenergic effect of mesaton was found to depend on the bending angle and the initial blood pressure level.
在麻醉大鼠中，当身体弯曲30度和45度时，在初始血压超过95毫米汞柱的情况下，收缩压和舒张压之间呈反向线性关系，而在初始血压低于95毫米汞柱时，这种关系是正向的。当身体弯曲60度时，这种关系是正向的，且仅在初始血压低于95毫米汞柱时出现。美速胺在直立位时的升压作用直接取决于初始血压水平。心输出量的变化与初始血压之间不存在任何相关性。发现动脉系统对直立位和美速胺肾上腺素能效应的反应性变化的方向和程度取决于弯曲角度和初始血压水平。
