• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Nonneurotropic adenovirus: a vector for gene transfer to the brain and gene therapy of neurological disorders.

作者信息

Lowenstein Pedro R, Suwelack Donata, Hu Jinwei, Yuan Xianpeng, Jimenez-Dalmaroni Maximiliano, Goverdhana Shyam, Castro Maria G

机构信息

Gene Therapeutics Research Institute, Cedars-Sinai Medical Center, Department of Medicine, UCLA, Los Angeles, California 90048, USA.

出版信息

Int Rev Neurobiol. 2003;55:3-64. doi: 10.1016/s0074-7742(03)01001-8.

DOI:10.1016/s0074-7742(03)01001-8
PMID:12968530
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2902245/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd54/2902245/af81c66623f3/nihms-201970-f0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd54/2902245/54cab21d7764/nihms-201970-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd54/2902245/6ddfa5e294f4/nihms-201970-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd54/2902245/b60ebc89d3b9/nihms-201970-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd54/2902245/9ccfd0e1676d/nihms-201970-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd54/2902245/457aad40be65/nihms-201970-f0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd54/2902245/af81c66623f3/nihms-201970-f0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd54/2902245/54cab21d7764/nihms-201970-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd54/2902245/6ddfa5e294f4/nihms-201970-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd54/2902245/b60ebc89d3b9/nihms-201970-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd54/2902245/9ccfd0e1676d/nihms-201970-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd54/2902245/457aad40be65/nihms-201970-f0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd54/2902245/af81c66623f3/nihms-201970-f0006.jpg

相似文献

1
Nonneurotropic adenovirus: a vector for gene transfer to the brain and gene therapy of neurological disorders.非嗜神经性腺病毒：一种用于向脑部进行基因转移及神经系统疾病基因治疗的载体。
Int Rev Neurobiol. 2003;55:3-64. doi: 10.1016/s0074-7742(03)01001-8.
2
Immune responses to adenovirus and adeno-associated vectors used for gene therapy of brain diseases: the role of immunological synapses in understanding the cell biology of neuroimmune interactions.对用于脑部疾病基因治疗的腺病毒和腺相关载体的免疫反应：免疫突触在理解神经免疫相互作用细胞生物学中的作用。
Curr Gene Ther. 2007 Oct;7(5):347-60. doi: 10.2174/156652307782151498.
3
Biology of adenovirus and its use as a vector for gene therapy.腺病毒生物学及其作为基因治疗载体的应用。
Hum Gene Ther. 2004 Nov;15(11):1022-33. doi: 10.1089/hum.2004.15.1022.
4
Adenovirus-mediated gene transfer to the brain: methodological assessment.腺病毒介导的基因向脑内转移：方法学评估
J Neurosci Methods. 1997 Jan;71(1):77-84. doi: 10.1016/s0165-0270(96)00128-8.
5
Adenovirus vectors and subviral particles for protein and peptide delivery.腺病毒载体和亚病毒颗粒用于蛋白质和肽类的递呈。
Curr Gene Ther. 2012 Oct;12(5):362-73. doi: 10.2174/156652312802762563.
6
Adenovirus-mediated gene transfer to liver.腺病毒介导的基因转移至肝脏。
Adv Drug Deliv Rev. 2001 Mar 1;46(1-3):205-9. doi: 10.1016/s0169-409x(00)00125-3.
7
Adenovirus vectors for gene delivery.用于基因递送的腺病毒载体。
Curr Opin Biotechnol. 1999 Oct;10(5):440-7. doi: 10.1016/s0958-1669(99)00007-5.
8
Adenovirus vectors for gene therapy, vaccination and cancer gene therapy.腺病毒载体用于基因治疗、疫苗接种和癌症基因治疗。
Curr Gene Ther. 2013 Dec;13(6):421-33. doi: 10.2174/1566523213666131125095046.
9
Adeno-associated virus vector-mediated gene transfer to somatic cells in the central nervous system.腺相关病毒载体介导的基因转移至中枢神经系统的体细胞。
Adv Virus Res. 2000;55:507-28. doi: 10.1016/s0065-3527(00)55015-5.
10
Barriers to systemic application of virus-based vectors in gene therapy: lessons from adenovirus type 5.基于病毒的载体在基因治疗中全身应用的障碍：来自5型腺病毒的经验教训。
Virus Genes. 2017 Oct;53(5):692-699. doi: 10.1007/s11262-017-1498-z. Epub 2017 Jul 28.

引用本文的文献

1
Engineered mitochondrial ferritin as a magnetic resonance imaging reporter in mouse olfactory epithelium.工程化线粒体铁蛋白作为小鼠嗅上皮磁共振成像报告基因。
PLoS One. 2013 Aug 30;8(8):e72720. doi: 10.1371/journal.pone.0072720. eCollection 2013.
2
Viral strategies for studying the brain, including a replication-restricted self-amplifying delta-G vesicular stomatis virus that rapidly expresses transgenes in brain and can generate a multicolor golgi-like expression.用于研究大脑的病毒策略，包括一种复制受限的自我扩增δ-G 水疱性口炎病毒，该病毒可在大脑中快速表达转基因，并能产生多色高尔基体样表达。
J Comp Neurol. 2009 Oct 20;516(6):456-81. doi: 10.1002/cne.22131.
3
Regulatable gene expression systems for gene therapy.用于基因治疗的可调控基因表达系统。
Curr Gene Ther. 2006 Aug;6(4):421-38. doi: 10.2174/156652306777934829.
4
Human gene therapy and imaging in neurological diseases.人类基因治疗与神经疾病成像
Eur J Nucl Med Mol Imaging. 2005 Dec;32 Suppl 2(Suppl 2):S358-83. doi: 10.1007/s00259-005-1960-3.
5
Regulatable gene expression systems for gene therapy applications: progress and future challenges.用于基因治疗应用的可调控基因表达系统：进展与未来挑战
Mol Ther. 2005 Aug;12(2):189-211. doi: 10.1016/j.ymthe.2005.03.022.

本文引用的文献

1
Gene transfer into rat brain using adenoviral vectors.使用腺病毒载体将基因导入大鼠脑内。
Curr Protoc Neurosci. 2001 May;Chapter 4:Unit 4.24. doi: 10.1002/0471142301.ns0424s13.
2
Progress and challenges in viral vector-mediated gene transfer to the brain.病毒载体介导的基因转移至大脑的研究进展与挑战
Curr Opin Mol Ther. 2002 Aug;4(4):359-71.
3
Transductional targeting with recombinant adenovirus vectors.重组腺病毒载体的转导靶向
Curr Gene Ther. 2002 Sep;2(3):323-39. doi: 10.2174/1566523023347823.
4
Tropism-modified adenoviral and adeno-associated viral vectors for gene therapy.用于基因治疗的嗜性修饰腺病毒和腺相关病毒载体
Curr Gene Ther. 2002 Sep;2(3):273-93. doi: 10.2174/1566523023347797.
5
Gene therapy of ovarian cancer.卵巢癌的基因治疗
Curr Womens Health Rep. 2002 Feb;2(1):39-46.
6
Gene therapy for restenosis: current status.再狭窄的基因治疗：现状
Drugs. 2002;62(11):1575-85. doi: 10.2165/00003495-200262110-00001.
7
Separating fact from fiction: assessing the potential of modified adenovirus vectors for use in human gene therapy.区分事实与虚构：评估修饰腺病毒载体用于人类基因治疗的潜力。
Curr Gene Ther. 2002 May;2(2):111-33. doi: 10.2174/1566523024605618.
8
Vector delivery methods and targeting strategies for gene therapy of brain tumors.脑肿瘤基因治疗的载体递送方法和靶向策略。
Curr Gene Ther. 2001 Nov;1(4):367-83. doi: 10.2174/1566523013348445.
9
Herpes simplex virus vectors for the nervous system.用于神经系统的单纯疱疹病毒载体。
Curr Gene Ther. 2001 Nov;1(4):339-58. doi: 10.2174/1566523013348346.
10
Rate limiting steps of AAV transduction and implications for human gene therapy.腺相关病毒转导的限速步骤及其对人类基因治疗的意义。
Curr Gene Ther. 2001 Jul;1(2):137-47. doi: 10.2174/1566523013348788.