Kaul S M, Raina V K, Joshi R D, Koya C N, Kumar A, Verghese T
National Institute of Communicable Diseases, Sham Nath Marg, Delhi.
J Commun Dis. 1992 Mar;24(1):16-9.
A filariasis survey carried out about eight years after achieving zero microfilaria (mf) rates following administration of diethylcarbamazine (DEC) medicated salt in the Kani hill tribe settlements in Quilon and Thiruvananthapuram districts of Kerala State revealed that there was no reappearance of Brugia malayi infection in the experimental areas. Mf rates were maintained at zero level in the experimental villages, while in the control villages, 2.9 per cent mf positives were observed. Mansonia (Mansonioides) uniformis dissected did not reveal filarial infection. It is concluded that DEC medicated salt regime in the experimental areas of Kani hill tribe settlements has been successful in effectively interrupting B. malayi transmission. Pilot studies in other B. malayi endemic areas of India using DEC medicated salt regime with the objective of eliminating B. malayi transmission are advocated, since the parasite has a restricted distribution in India and is already showing a declining trend.
在喀拉拉邦奎隆和特里凡得琅地区的卡尼山地部落定居点，在服用乙胺嗪（DEC）药盐后实现微丝蚴（mf）率为零约八年后进行的丝虫病调查显示，试验区未再次出现马来布鲁线虫感染。试验区村庄的mf率维持在零水平，而对照村庄观察到2.9%的mf阳性。解剖的同型曼蚊（类曼蚊属）未显示丝虫感染。得出的结论是，卡尼山地部落定居点试验区的DEC药盐方案成功地有效阻断了马来布鲁线虫的传播。鉴于该寄生虫在印度分布有限且已呈下降趋势，提倡在印度其他马来布鲁线虫流行地区使用DEC药盐方案开展试点研究，以消除马来布鲁线虫传播。
