Aminoacetonitrile (AAN)prevents connective proliferation in rat liver induced by tetrachlorcarbon. Continuous concomitant administration of AAN.

A total dose of 10 g/kg body weight of aminoacetonitrile distributed almost evenly over 35 days prevents formation of connective bands and damage of hepatocytes in the liver of rats submitted to CCl4 inhalations at a partial pressure of 1/6 atm, eight times within the same interaval. Control animals exhibited the usual pattern of CCl4 injury.