Styer Aaron K, Cekleniak Natalie A, Legedza Anna, Mutter George L, Hornstein Mark D
Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.
Fertil Steril. 2003 Sep;80(3):584-9. doi: 10.1016/s0015-0282(03)00976-2.
To study patient characteristics associated with the preferences for the disposition of cryopreserved semen and embryos in the event of death or divorce.
Retrospective exploratory study.
Tertiary care academic medical center.
PATIENT(S): One hundred twelve men banking sperm, 54 female patients (partners of men banking sperm) undergoing in vitro fertilization (IVF), and 112 women undergoing IVF who were not partners of men banking sperm.
INTERVENTION(S): Male patients banking sperm and couples undergoing IVF completed a standard consent form detailing their desired dispositions (disposal or release to a surviving party) of cryopreserved sperm and embryos in the event of death or divorce.
MAIN OUTCOME MEASURE(S): Effect of marital status, age, reason for sperm banking, infertility diagnosis, partner status (single or significant-other partner) on sperm, and embryo disposition choice.
RESULT(S): In the event of death, married men were 5.5 times more likely to release banked sperm to a surviving party than were single men. The estimated odds of giving sperm to a survivor were 1.07 times greater with every 1-year increase in age. The choice of sperm disposal was significantly related to the banking reason for the case of banking prior to chemotherapy and/or radiation for malignancy. In the case of male death, the decisions of couples undergoing IVF for embryo disposition agreed with choices of male patients for sperm disposition approximately 33% of the time more often than by chance alone.
CONCLUSION(S): Decisions surrounding disposition of cryopreserved sperm are significantly associated with marital status, age, and reason for banking sperm. Respective choices of sperm and embryo disposition in couples undergoing IVF were similar in the situation of male death.
研究在死亡或离婚情况下，与冷冻精液和胚胎处置偏好相关的患者特征。
回顾性探索性研究。
三级医疗学术医学中心。
112名储存精子的男性、54名接受体外受精（IVF）的女性患者（储存精子男性的伴侣）以及112名接受IVF但不是储存精子男性伴侣的女性。
储存精子的男性患者和接受IVF的夫妇填写一份标准同意书，详细说明他们在死亡或离婚情况下对冷冻精子和胚胎的期望处置方式（处置或交给在世一方）。
婚姻状况、年龄、储存精子的原因、不孕诊断、伴侣状况（单身或重要伴侣）对精子和胚胎处置选择的影响。
在死亡情况下已婚男性将储存精子交给在世一方的可能性是单身男性的5.5倍。年龄每增加1岁，将精子交给幸存者的估计几率就会增加1.07倍。对于因恶性肿瘤化疗和/或放疗前储存精子的情况，精子处置的选择与储存原因显著相关。在男性死亡的情况下，接受IVF的夫妇对胚胎处置的决定与男性患者对精子处置的选择相符的概率比随机情况高出约33%。
围绕冷冻精子处置的决定与婚姻状况、年龄和储存精子的原因显著相关。在男性死亡的情况下，接受IVF的夫妇中精子和胚胎处置的各自选择相似。
